In hypercatabolic diseases such as AIDS, Toxic Shock Syndrome and septicemia, the dud of.?

inhibition of inflammatory mediators by cortisol within the body results in a hypercatabolic state. However surrounded by Cushing's syndrome, excess cortisol in the body cause a hypercatabolic effect. Explain the contradiction in the performance of cortisol with relation to hypercatabolism? Cortisol cause hypercatabolism in consistent parts of the body and not in others. Also, surrounded by iatrogenic Cushing's, the main culprit is artificial gluccocorticoids (of which at hand are several different types that may act on different body parts within different ways). I have see patients on predinisone with tremendously thin skin, muscle wasting, etc but beside build up of body fat because gluccocorticoids stimulate glucconeogensis.